Back in 1922, government employees Townsend Whelen and James V. Howe of Springfield Armory developed the .400 Whelen, a wildcat formed by .30-06configuration. During that same year, while Whelen was away on a hunting trip, Howe decided to neck the .400 on down to .35 caliber and thus created what he decided to call the .35 Whelen. With 3500 foot/pounds of energy, the .35 Whelen is more powerful than the .30-06, and quite capable of taking all North American big game. For deer size game, bullets weighing 200 to 250 grains are the best choices. With �the possible exception the Nosler225 grain Partition, heavier bullets are better choices for larger game. For elk, moose, and bear, the Speerand Barnes250 grain spitzers at 2500 fps deliver a ton of energy at 300 yards. When zeroed three inches high at 100 yards, both have a point blank range of about325 yards on a bull elk's vital area. 

This text is based on information from “Cartridges of the World”, Hodgdon reloading manual, the cartridge designer and/or own resources.